I wasn't certain that it would interest that many people, but I was intrigued that the original photo mentioned how small the suture was. But I knew there was much smaller suture in routine use throughout the world of micro-surgery. Imagine suturing an artery only 2 mm in diameter to restore blood flow in a severed finger, or a vas deferens ( approximately 1mm diameter ) to restore fertility.
I found your link about mathmatical modelling of knots interesting too. Secure knots have always been of great interest to surgeons, fishermen (of both sexes), sailors, crane operators, and engineers, and even state sanctioned hangmen to mention just a few careers affected by secure knots.
One aspect that wasn't mentioned about knot security is the type of line being tied - standard hemp rope, nylon rope braided or twisted, monofiliament ( like nylon suture or fishing line) and synthetic filiaments like kevlar or braided synthetic fishing line like SpiderWire. Different line types perform better with different knots - some fishing knots even add a drop of Crazy Glue - cyanoacrylic
The Apple App store offers some great Apps with videos for how to tie many common, and uncommon, knots. I'm not sure how to post the links here but here are a couple names - The Knot guide, and Animated Knots by Grog, demonstrating step by step how good knots are assembled -
I always have to review how to tie a Bimini Twist, a favorite of the offshore fishing crowd for its robustness, security and strength - but a knot I use infrequently, but prefer sometimes.
Folks should take a gander at the images offered in the OP's original link - some very good images created by real scientists.