For those not familiar with a specific airplane, a flightdeck will probably look really overwhelming. But that is why we get trained to fly a specific airplane.
Everything on the overhead panel, are system settings that we set before the flight mainly; During the flight we hardly touch them. Usually only once per flight to select a different fueltank/engine configuration.
The glareshield is mainly autopilot stuff. Below that the screens with all the information, and on the pedestal mostly engine controls and communication/navigation systems. That really is about it.
The systems got a lot more complex (and we have more systems) so we have more buttons and information that the WWII era planes. But if you look at the screen with the artificial horizon, it also shows you things like speed, altitude, heading. The same things as the WWII planes, in a modern but not dissimilar presentation.
I have an uncle who retired from flying last year. He was a pilot at United Airlines for 35+ years. He loved his job. My understanding is these 747s are much more automated and while it's much more convenient for the pilots and all, he seemed to miss the days when pilots had more manual control over their planes. It's a pretty interesting and exciting profession. Really an awesome shot! Thanks for sharing!
A lot of things in this plane (especially this version) are automated, more so than the older versions. It has to be (since we lost the flight engineer and we are only with two now), but also because it is safer; We as humans are prone to several problems that a computer is not prone to. Our jobs, and your uncle will surely have noticed, have changed over the years from being a pilot/flightengineer/mechanic combination to a pilot/systemsmonitoring/systemsoperator type of job. (The automation in itself can create problems as wel, but that is a whole different story).